Unexplained infertility — St. Louis, MO

Unexplained infertility means the standard workup — ovulation, tubes, semen analysis, ovarian reserve — found no cause. It is a diagnosis of exclusion, and it is common. It does not mean nothing is wrong; it means today's tests can't see what is.

The evidence-backed path is usually stepped: a few cycles of ovulation induction with IUI, then IVF if those fail. Reasonable clinics differ on how fast to escalate — what matters is that the plan has a defined number of attempts and a decision point, not open-ended repetition.

Fertility clinics in St. Louis, MO

The share shown for each clinic is the percentage of its cycles with an unexplained-factor diagnosis.

• Fertility and Reproductive Medicine Center, at Washington University School of Medicine and Barnes-Jewish Hospital ranked #84 nationally · 12% of cycles: unexplained factor
• STL Fertility ranked #270 nationally · 27% of cycles: unexplained factor
• Center for Reproductive Medicine & Robotic Surgery not rated · 0.5% of cycles: unexplained factor

What to ask at a consult

• What did my workup actually rule out, and what wasn't tested?
• How many IUI cycles before IVF, and what success rate do you expect from each step for my age?
• At what point would you change the plan?

Costs are a first-class question for treatment — see what IVF costs and how to pay less and whether insurance must cover treatment in Missouri.

Outcome data: CDC NASS 2022 Final ART Summary. Success rates vary with patient age, diagnosis, and clinic patient-selection practices; comparisons across clinics may not be meaningful (CDC). This page is general information, not medical advice.